| 产品详情 |
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| Antigenic Specificity | LIMS1 |
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| Clone | 5G7 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1/200 - 1/400, Immunocytochemistry: 1:200-1:1000, Immunofluorescence: 1/200 - 1/1000, Western Blot: 1/500 - 1/2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LIMS1 Monoclonal Antibody (5G7). The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. |
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| Immunogen | n/a |
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| Other Names | PINCH, PINCH-1, PINCH1, LIM and senescent cell antigen-like-containing domain protein 1; particularly interesting new Cys-His protein 1; renal carcinoma antigen NY-REN-48 |
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| Gene, Accession # | Entrez: 3987; Uniprot: P48059 |
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| Catalog # | MA5-15876 |
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| Price | |
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| Order / More Info | LIMS1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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