产品详情 |
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Antigenic Specificity | c-Kit |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | canine, human, rat |
Isotype | n/a |
Format | purified |
Size | 500 µL |
Concentration | n/a |
Applications | Flow Cytometry: 2 µg/test, Immunocytochemistry: 1:10-1:200, Immunofluorescence: 1:10-1:200, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:50-1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | c-Kit Polyclonal Antibody. Recognizes a protein of 145kDa, which is identified as CD117/p145kit. This rabbit polyclonal antibody does not interfere with the binding of SCF to c-kit. It precipitates both the unoccupied as well as the occupied form of c-kit. The binding of the stem cell factor (SCF) to the c-kit-encoded receptor tyrosine kinase (Type III) stimulates a variety of biochemical responses that culminate in cellular proliferation, migration, or survival. C-kit plays an important role in hematopoiesis, melanogenesis, and gametogenesis. This antibody is excellent for staining of formalin-fixed, paraffin-embedded tissues. |
Immunogen | n/a |
Other Names | C-Kit, CD117, PBT, SCFR, mast/stem cell growth factor receptor Kit, p145 c-kit, piebald trait protein, proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, soluble KIT variant 1, tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein, ckit |
Gene, Accession # | Entrez: 3815, 403811, 64030; Uniprot: O97799, P10721 |
Catalog # | PA5-16770 |
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Order / More Info | c-Kit Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 23892469, 25758746 |
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