| 产品详情 |
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| Antigenic Specificity | DcR3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1 µg/mL, Western Blot: 0.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DcR3 Polyclonal Antibody. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively,. Unlike DcR1 and DcR2, DcR3 is a soluble rather than a membrane associated molecule. DcR3 binds to FasL and LIGHT and inhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and colon carcinomas an |
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| Immunogen | n/a |
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| Other Names | hCG_2044836, DCR3, DJ583P15.1.1, M68, M68E, TR6; decoy receptor 3; decoy receptor for Fas ligand; tumor necrosis factor receptor superfamily member 6B |
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| Gene, Accession # | Entrez: 8771; Uniprot: O95407 |
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| Catalog # | PA5-19924 |
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| Price | |
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| Order / More Info | DcR3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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