| 产品详情 |
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| Antigenic Specificity | L3MBTL1 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | L3MBTL1 Monoclonal Antibody. L3MBTL1 is the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. L3MBTL1 is localized to condensed chromosomes in mitotic cells and overexpression of this protein in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. L3MBTL1 represents a polycomb group gene the encoded protein functions to regulate gene activity, likely via chromatin modification. Polycomb group protein specifically recognizes and binds mono- and dimethyllysine residues on target proteins, thereby acting as a reader of a network of post-translational modifications. Alternative |
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| Immunogen | n/a |
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| Other Names | H-L(3)MBT, L3MBTL, dJ138B7.3, l(3)mbt protein homolog, lethal (3) malignant brain tumor l(3), lethal(3)malignant brain tumor-like protein 1 |
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| Gene, Accession # | Entrez: 26013; Uniprot: Q9Y468 |
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| Catalog # | 730022 |
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| Price | |
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| Order / More Info | L3MBTL1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 26121405 |
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