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Product Name | Calphostin C |
Description | Potent, selective and photo-dependent inhibitor of protein kinase C that targets the regulatory domain (IC50 = 50 nM). Displays > 1000-fold selectivity over other protein kinases such as cAMP-dependent protein kinase and tyrosine-specific protein kinase. Inhibits cell proliferation of malignant glioma cells in light-treated conditions in vitro (IC50 ~ 40 - 60 nM). Also an antagonist of the Tcf/β-catenin complex. Purity 98%. MW (observed): 790.76 |
Size | 100 ug |
Concentration | n/a |
Applications | n/a |
Other Names | (1R)-2-[12-[(2R)-2-(Benzoyloxy)propyl]-3,10-dihydro-4,9-dihydroxy-2,6,7,11-tetramethoxy-3,10-dioxo-1-perylenyl]-1-methylethylcarbonic acid 4-hydroxyphenyl ester. UCN 1028C, PKF 115584 |
Gene, Accession, CAS # | CAS: 121263-19-2 |
Catalog # | 1626/100U |
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Order / More Info | Calphostin C from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 19724676, 23048072, 25052197, 25439010, 26222156 |
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