| 产品详情 |
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| Antigenic Specificity | LRP6 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB, IHC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LRP6 Antibody is a Rabbit Polyclonal antibody against LRP6. This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined. |
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| Immunogen | A synthetic peptide of human LRP6. |
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| Other Names | ADCAD2; Low Density Lipoprotein Receptor Related Protein 6; LRP6; LRP-6; low density lipoprotein receptor-related protein 6; low density lipoprotein-related protein 6; FLJ90062; FLJ90421; Low-density lipoprotein receptor-related protein 6 |
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| Gene, Accession # | LRP6, Gene ID: 4040, SwissProt: O75581 |
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| Catalog # | abx000776 |
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| Price | |
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| Order / More Info | LRP6 Antibody from ABBEXA |
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| Product Specific References | n/a |
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