| 产品详情 |
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| Antigenic Specificity | LRP6 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB, IHC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LRP6 is essential for the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. The interaction with DKK1 blocks LRP6-mediated Wnt/beta catenin signaling via LRP6 removal via Kremen proteins-mediated endocytosis. This LRP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1531-1560 amino acids from the C-terminal region of human LRP6. |
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| Immunogen | Human LRP6. |
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| Other Names | ADCAD2; Low Density Lipoprotein Receptor Related Protein 6; LRP6; LRP-6; low density lipoprotein receptor-related protein 6; low density lipoprotein-related protein 6; FLJ90062; FLJ90421; Low-density lipoprotein receptor-related protein 6 |
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| Gene, Accession # | Accession: NP_002327.2, SwissProt: O75581 |
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| Catalog # | abx032705 |
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| Price | |
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| Order / More Info | LRP6 Antibody from ABBEXA |
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| Product Specific References | n/a |
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| 产品资料 |
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