| Edit |   |
| Antigenic Specificity | LRP5 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | purified |
| Size | 100 µg |
| Concentration | 1.0 mg/ml |
| Applications | ELISA, WB, FCM. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. |
| Immunogen | Purified recombinant fragment of human LRP5 expressed in E. Coli. |
| Other Names | HBM; LR3; OPS; EVR1; EVR4; LRP7; OPPG; BMND1; OPTA1; VBCH2; Low Density Lipoprotein Receptor Related Protein 5; LRP5; Low-density lipoprotein receptor-related protein 5; LRP-5; low density lipoprotein receptor-related protein 5; HGNC:6697; low density lipoprotein receptor-related protein 7; osteoporosis pseudoglioma syndrome; exudative vitreoretinopathy 1 |
| Gene, Accession # | LRP5, Gene ID: 4041, SwissProt: O75197 |
| Catalog # | abx012102 |
| Price | |
| Order / More Info | LRP5 Antibody from ABBEXA |
| Product Specific References | n/a |