| 产品详情 |
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| Antigenic Specificity | KMT2D |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:200-1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | KMT2D Polyclonal Antibody. KMT2D is a histone methyltransferase that methylates Lys-4 of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. KMT2D acts as a coactivator for estrogen receptors by being recruited by ESR1 and activating transcription. KMT2D is involved in chromatin organization, chormatin silencing, oocyte growth, oogenesis, and a positive regulation of cell proliferation. Mutations in the KMT2D gene cause Kabuki syndrome (KABUK1) which results in congential mental retardation syndrome. |
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| Immunogen | n/a |
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| Other Names | Lysine (K)-Specific Methyltransferase 2D, ALR, MLL2, MLL4 |
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| Gene, Accession # | Entrez: 8085; Uniprot: O14686 |
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| Catalog # | PA5-57490 |
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| Price | |
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| Order / More Info | KMT2D Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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