| 产品详情 |
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| Antigenic Specificity | BAG4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BAG4 is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. This BAG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 381-409 amino acids from the C-terminal region of human BAG4. |
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| Immunogen | Human BAG4. |
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| Other Names | BAG family molecular chaperone regulator 4; BAG-4; BAG-family molecular chaperone regulator-4; BAG4; Bcl-2-associated athanogene 4; BCL2-associated athanogene 4; Silencer of death domains; SODD |
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| Gene, Accession # | BAG4, SwissProt: O95429 |
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| Catalog # | abx028746 |
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| Price | |
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| Order / More Info | BAG4 Antibody from ABBEXA |
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| Product Specific References | n/a |
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| 产品资料 |
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