| 产品详情 |
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| Antigenic Specificity | DKK3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DKK3 Polyclonal Antibody. DKK3, like DKK1, DKK2, and DKK4, possesses an N-terminal signal peptide and 2 conserved cysteine-rich domains, which are separated by a linker region and contain 10 cysteine residues each. The second cysteine region has a putative lipid-binding function that may facilitate WNT/DKK interactions at the plasma membrane. The linker region contains 50 to 55 amino acids in DKK1, DKK2, and DKK4, whereas in DKK3 it contains only 12 amino acids. All DKKs have several potential sites for cleavage by furin-type proteases. Northern blot analysis revealed wide expression of the DKK3 transcript, with highest expression in heart, brain, and spinal cord. In situ hybridization reveals highest expression in mouse brain, eye, and hea |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 27122; Uniprot: Q9UBP4 |
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| Catalog # | PA5-11618 |
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| Price | |
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| Order / More Info | DKK3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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