| 产品详情 |
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| Product Name | RO8994 |
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| Description | An inhibitor of the protein-protein interaction between MDM2 and p53 (IC50 = 5 nM in a p53-MDM2 HTRF binding assay); inhibits the proliferation of SJSA-1, RKO, and HCT116 cells (average IC50 = 20 nM); increases apoptosis in SJSA-1 cells in a concentration-dependent manner; reduces tumor growth and induces tumor regression in an SJSA-1 osteosarcoma mouse xenograft model at 1.56 and 6.25 mg/kg, respectively. |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | CAS: 1309684-94-3 |
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| Catalog # | 25674-25 |
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| Price | |
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| Order / More Info | RO8994 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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