产品详情 |
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Antigenic Specificity | Fascin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Fascin Polyclonal Antibody. Fascin 1 encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. |
Immunogen | n/a |
Other Names | SNL, FAN1, HSN, fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus), FSCN1, p55 |
Gene, Accession # | Entrez: 14086, 6624; Uniprot: Q16658, Q61553 |
Catalog # | PA5-78171 |
Price | |
Order / More Info | Fascin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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