| 产品详情 |
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| Product Name | Antazoline (hydrochloride) |
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| Description | A histamine H1 receptor antagonist (Ki = 38.4 nM in cell membranes expressing human recombinant H1 receptors); reduces histamine-induced IL-6 and IL-8 production in human conjunctival epithelial cells (IC50s = 1 and 0.652 µM, respectively); prevents anaphylaxis in rabbits sensitized to egg albumin and increases survival in a guinea pig model of histamine-induced bronchospasm; eliminates atrial fibrillation induced by acetylcholine and isoproterenol in isolated rabbit hearts by increasing the atrial effective refractory period and interatrial conduction time in a dose-dependent manner; binds to NMDA receptors (Ki = 13 µM) and reduces glutamate-induced toxicity in cerebellar granule cells (EC50 = 13 µM) |
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| Size | 1 g |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-(N-Benzylanilinomethyl)-2-imidazoline Hydrochloride |
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| Gene, Accession, CAS # | CAS: 2508-72-7 |
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| Catalog # | 23415-1 |
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| Order / More Info | Antazoline (hydrochloride) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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