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| Antigenic Specificity | CCR2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | DyLight 488 conjugate |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:50, Immunocytochemistry: 1:50, Immunofluorescence: 1:50 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CCR2 Polyclonal Antibody, DyLight 488. CCR2, a Chemokine Receptor, is a regulator of monocyte/macrophage traffickings and is upregulated in response to inflammation. Resistance to HIV-1 infection or delayed progression to AIDS may be linked to CCR2 polymorphisms. The ligand for CCR2 is monocyte chemoattractant protein (MCP-1), a chemokine produced by endothelial cells, smooth muscle cells, and macrophages. Activation of monocytes by MCP-1 may mediate the monocytic infiltration of tissues in atherosclerosis (Boring et al., 1998) and other inflammatory disorders including rheumatoid arthritis, alveolitis, and tumor infiltration. Two isoforms are produced by alternative splicing. CCR2 has been reported to be expressed in a wide variety of tiss |
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| Immunogen | n/a |
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| Other Names | hCG_14621, CC-CKR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R, C-C CKR-2, C-C chemokine receptor type 2, CCR-2, MCP-1 receptor, monocyte chemoattractant protein 1 receptor, monocyte chemotactic protein 1 receptor |
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| Gene, Accession # | Entrez: 12772, 729230; Uniprot: P41597, P51683 |
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| Catalog # | PA5-23046 |
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| Price | |
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| Order / More Info | CCR2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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