产品详情 |
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Antigenic Specificity | CCR7 |
Clone | 4B12 |
Host Species | Rat |
Reactive Species | human, mouse |
Isotype | IgG2a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Flow Cytometry: 5 µg/1X10^6 cells, Western Blot: 1:250-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CCR7 Monoclonal Antibody (4B12). CCR7 is a member of the G protein coupled receptor family, which is a subfamily of chemokines. CCR7 was identified to be induced by the Epstein Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. CCR7 has been reported to be expressed in blood, bone marrow, lymph node, and intestine. CCR7 is particularly expressed in lymphoid tissues and in activated B and T lymphocytes and has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. ESTs have been isolated from blood, embryo, lymph node, and thymus librari |
Immunogen | n/a |
Other Names | Chemokine (C-C Motif) Receptor 7, CMKBR7, EBI1, CCR-7, Epstein-Barr Virus-Induced G-Protein Coupled Receptor 1, MIP-3 Beta Receptor , CD197 |
Gene, Accession # | Entrez: 1236, 12775; Uniprot: P32248, P47774 |
Catalog # | MA1-163 |
Price | |
Order / More Info | CCR7 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 27791035 |
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