Edit |   |
Antigenic Specificity | FAPP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FAPP2 Polyclonal Antibody. Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans-Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation. |
Immunogen | n/a |
Other Names | PLEKHA8; FAPP2; phosphoinositol 4-phosphate adaptor protein-2; MGC3358; pleckstrin homology domain containing; family A (phosphoinositide binding specific) member 8 |
Gene, Accession # | Entrez: 84725; Uniprot: Q96JA3 |
Catalog # | PA5-67238 |
Price | |
Order / More Info | FAPP2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |