产品详情 |
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Antigenic Specificity | CD45RA |
Clone | SPM504 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | purified |
Size | 500 µL |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:200 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45RA Monoclonal Antibody (SPM504). CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells. CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing and these isoforms differ in their extracellular domains, however, they share identical transmembrane and cytoplasmic domains. CD45 isoforms differ in their ability to t |
Immunogen | n/a |
Other Names | B220, CD45, CD45R, GP180, LCA, LY5, T200 |
Gene, Accession # | Entrez: 5788; Uniprot: P08575 |
Catalog # | MA5-16341 |
Price | |
Order / More Info | CD45RA Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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