| 产品详情 |
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| Product Name | DEL-22379 |
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| Description | An inhibitor of ERK dimerization (IC50 = ~0.5 µM for disruption of EGF-induced co-immunoprecipitation of ERK); has no effect on ERK phosphorylation or kinase activity (IC50s = >10 µM); inhibits cell growth in a panel of melanoma and colorectal cancer cell lines (IC50s = 150-400 nM); inhibits ERK dimerization in liver extract and tumor tissue and inhibits tumor progression in an A375 mouse xenograft model at 15 mg/kg; reduces tumor growth in a BRAF mutant colorectal cancer PDX mouse model |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | DEL22379 A-375 endothelial growth factor coimmunoprecipitation |
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| Gene, Accession, CAS # | CAS: 181223-80-3 |
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| Catalog # | 22433-5 |
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| Price | |
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| Order / More Info | DEL-22379 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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