产品详情 |
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Antigenic Specificity | CCNE2/Cyclin E2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 20 µL |
Concentration | n/a |
Applications | Western Blot: 1:1,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CCNE2/Cyclin E2 Polyclonal Antibody. Cyclin E2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. The human Cyclin E2 gene encodes a 404 amino acid protein that is most closely related to Cyclin E. Cyclin E2 mRNA levels peaks at the G1 / S transition. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27 (Kip1) and p21 (Cip1). Cyclin E2 / Cdk2 phosphorylates histone H1 in vitro. G1 cyclin E controls the initiation of DNA synthesis by activating CDK2. Abnormally high levels of cyclin E expression have frequently been observed in human cancers. Unlike Cyclin E1, which is expressed in great majority of prolif |
Immunogen | n/a |
Other Names | CYCE2 |
Gene, Accession # | Entrez: 12448, 9134; Uniprot: O96020, Q9Z238 |
Catalog # | A305-275A-T |
Price | |
Order / More Info | CCNE2/Cyclin E2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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