| 产品详情 |
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| Product Name | Romidepsin |
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| Description | A natural bicyclic depsipeptide that selectively inhibits class I HDACs (IC50s = 53, 39, 53, and 26 nM, for HDAC1, 2, 3, and 8, respectively) over HDAC4, 6, 7, and 9 (IC50s = 470, 330, 3,200, and 12,000 nM, respectively); has anti-cancer activities, particularly against certain T cell lymphomas; increases mRNA expression, histone acetylation, and the levels of proteins involved in NMDA receptor function in the brain of Shank3-deficient mice; rescues autism-like deficits in Shank3-deficient mice for at least three weeks following a dose of 0.25 mg/kg per day for three days |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FK228|FR901228|NSC 630176 |
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| Gene, Accession, CAS # | CAS: 128517-07-7 |
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| Catalog # | 17130-5 |
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| Price | |
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| Order / More Info | Romidepsin from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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