| 产品详情 |
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| Antigenic Specificity | MTM1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB, IHC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MTM1 is a member of a protein family that encodes tyrosine phosphatases. Myotubularin is required for muscle cell differentiation and mutations in MTM1 have been identified as being responsible for X-linked myotubular myopathy. MTM1 is a potent phosphatidylinositol 3-phosphate phosphatase (PI (3) P). Mutations in the MTM1 gene that cause human myotubular myopathy dramatically reduce the ability of the phosphatase to dephosphorylate PI (3) P. The findings provided evidence that myotubularin exerts its effects during myogenesis by regulating the cellular levels of the inositol lipid PI (3) P. This MTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MTM1. |
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| Immunogen | Human MTM1. |
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| Other Names | MTM1; CG2; Myotubularin; myotubularin 1; XLMTM; MTMX; myotubular myopathy 1; CNM; Phosphatidylinositol-3; 5-bisphosphate 3-phosphatase; Phosphatidylinositol-3-phosphate phosphatase |
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| Gene, Accession # | Accession: NP_000243.1, SwissProt: Q13496 |
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| Catalog # | abx032999 |
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| Price | |
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| Order / More Info | MTM1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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| 产品资料 |
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