| 产品详情 |
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| Antigenic Specificity | RNF20 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RNF20 Antibody is a Rabbit Polyclonal antibody against RNF20. The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). |
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| Immunogen | Recombinant protein of human RNF20. |
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| Other Names | BRE1; BRE1A; hBRE1; E3 ubiquitin-protein ligase BRE1A; RING finger protein 20; RNF20; BRE1-A; KAIA2779; Homolog of S. cerevisiae BRE1 |
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| Gene, Accession # | RNF20, Gene ID: 56254, SwissProt: Q5VTR2 |
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| Catalog # | abx001887 |
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| Price | |
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| Order / More Info | RNF20 Antibody from ABBEXA |
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| Product Specific References | n/a |
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