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Product Name | 15(R)-Iloprost |
Description | Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin.{3347} Iloprost binds with equal affinity to the human recombinant IP and EP receptors with a Ki of 11 nM.{8322} 15(R)-Iloprost is the ``unnatural'' or inverted C-15 epimer of iloprost. This transformation frequently attenuates the biological agonist activity of prostaglandin analogs by several orders of magnitude. There are no literature reports of the biological activity of 15(R)-iloprost. |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | analogs PGI2 prostaglandins prostacyclin unnatural C-15 epimers |
Gene, Accession, CAS # | CAS: 85026-51-3 |
Catalog # | 10043-10 |
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Order / More Info | 15(R)-Iloprost from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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