产品详情 |
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Antigenic Specificity | Lamin B2 |
Clone | E-3 |
Host Species | Mouse |
Reactive Species | chicken, human, mouse, rat |
Isotype | IgG1, kappa |
Format | Alexa Fluor 488 conjugate |
Size | 50 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-10 µg/mL, Immunofluorescence: 1-10 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Lamin B2 Monoclonal Antibody (E-3), Alexa Fluor 488. Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2. Recent evidence has revealed that mutations in A-type lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-type |
Immunogen | n/a |
Other Names | LAMB2, LMN2 |
Gene, Accession # | Entrez: 16907, 299625, 396222, 84823; Uniprot: P14732, P21619, Q03252 |
Catalog # | MA3-32100-A488 |
Price | |
Order / More Info | Lamin B2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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