| 产品详情 |
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| Product Name | PPOH |
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| Description | Arachidonic acid is converted by microsomal CYP450 enzymes to a variety of epoxides, ω-1 and ω-hydroxylated compounds via what is known as the epoxidase pathway.{313,403,823} PPOH is a selective inhibitor of the epoxygenation reactions catalyzed by specific CYP450 isozymes.{8589} PPOH inhibits the formation of arachidonate 11,12 epoxides by CYP4A2 and CYP4A3 enzymes with an IC50 value of 9 µM, but has effect on the formation of 20-HETE, the ω-hydroxylation product of CYP4A1.{8588} |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | selective epoxygenases inhibitors inhibits acetylenic fatty acids cytochromes CYP450-4A2 CYP450-4A3 CYP450-4A1 CYP-450-4A2 CYP-450-4A3 CYP-450-4A1 CYP-4A2 CYP-4A1 CYP-4A3 endocrinology |
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| Gene, Accession, CAS # | CAS: 206052-01-9 |
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| Catalog # | 75760-50 |
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| Price | |
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| Order / More Info | PPOH from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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