产品详情 |
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Antigenic Specificity | Neutrophil elastase |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | lyophilized |
Applications | Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Neutrophil elastase Polyclonal Antibody. Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Elastase 2 hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix following the protein's release from activated neutrophils. Elastase 2 may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella an |
Immunogen | n/a |
Other Names | Neutrophil elastase, Elastase-2, Leukocyte elastase, Elane, Ela2 |
Gene, Accession # | Entrez: 299606, 50701; Uniprot: Q3UP87 |
Catalog # | PA5-79198 |
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Order / More Info | Neutrophil elastase Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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