Edit |   |
Antigenic Specificity | LIME |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot: Assay dependent. |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | LIME Polyclonal Antibody. LIME (Lck-interacting molecule) is a new raft-associated adaptor protein involved in regulation of T cell activation by coreceptors. LIME becomes tyrosine phosphorylated after cross-linking of the CD4 or CD8 coreceptors. Phospho-LIME associates with the Src family kinase Lck and its negative regulator, Csk. Ectopic expression of LIME in Jurkat T cells results in an increase of Csk in lipid rafts, increased phosphorylation of Lck and higher Ca2+ response to CD3 stimulation. |
Immunogen | n/a |
Other Names | Lck-interacting molecule |
Gene, Accession # | Entrez: 54923; Uniprot: Q9H400 |
Catalog # | PA1-35994 |
Price | |
Order / More Info | LIME Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |