产品详情 |
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Product Name | Bendamustine (hydrochloride) |
Description | A DNA alkylating agent; inhibits growth of SKW-3, Reh, CML-T1, BV-173, and HL-60 leukemia cell lines (IC50s = 27.0, 28.6, 15.6, 20.8, and 57.7 µM, respectively) but not MCF-7 and MDA-MB-231 breast cancer cell lines (IC50s = >200 and >200 µM, respectively); kills B-CLL cells derived from naive and bendamustine-pretreated patients (LD50s= 6.8-8.3 and 3.8-4.9 mg/ml, respectively); inhibits tumor growth by 9% and 96% alone and in combination with ofatumumab, respectively, in a JVM-3 CLL mouse xenograft model (50 mg/kg) |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | SDX-105 |
Gene, Accession, CAS # | CAS: 3543-75-7 |
Catalog # | 23693-50 |
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Order / More Info | Bendamustine (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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