| 产品详情 |
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| Product Name | NMS-E973 |
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| Description | An HSP90 inhibitor (IC50 = 10 nM in a fluorescence polarization assay); decreases HER2 protein expression (IC50 = 110 nM) in BT474 breast cancer cells; inhibits the growth of a 16 cancer cell line panel (IC50s = 13-362 nM); reduces tumor growth by 74% in an A2780 mouse xenograft model at a dose of 60 mg/kg, i.v., per day for ten days; completely eradicates MOLM-13 acute myeloid leukemia tumors in a mouse xenograft model |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NMSE-973 NMSE973 HER-2 MOLM13 hsp-90 BT-474 AML human epidermal growth factor extracellular?signal?regulated kinase |
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| Gene, Accession, CAS # | CAS: 1253584-84-7 |
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| Catalog # | 22352-5 |
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| Price | |
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| Order / More Info | NMS-E973 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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