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Product Name | (±)5-HEPE |
Description | (±)5-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 5(S)-HEPE and 5(R)-HEPE. The biological activity of (±)5-HEPE is likely mediated by one of the individual isomers, most commonly the 5(S) isomer in mammalian systems. EPA can be metabolized to 5-HEPE in human and bovine neutrophils, and human eosinophils, which is further metabolized to 5-oxoEPE and LTB5.{11149,11166,11167} The 5-series metabolites of EPA, namely 5-HEPE, 5-oxoEPE, and LTB5, have significantly decreased biological effects compared to the arachidonic acid-derived metabolites.{11167} |
Size | 25 µg |
Concentration | n/a |
Applications | n/a |
Other Names | racemic hydroxy acids fatty EPA autoxidation (+/-)5-HEPEs eicosapentanoic (+/-)-HEPEs (+/-)HEPEs |
Gene, Accession, CAS # | CAS: 83952-40-3 |
Catalog # | 32200-25 |
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Order / More Info | (±)5-HEPE from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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