产品详情 |
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Antigenic Specificity | MEKK3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 20 µL |
Concentration | n/a |
Applications | Western Blot: 1:1,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MEKK3 Polyclonal Antibody. Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli including growth factors. The MEK kinases (also called MAP kinase kinase kinases) phosphorylate and activate the MAP kinases, including ERK, JNK and p38. The MEK kinases characterized to date include Raf-1, Raf-B, MOS, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4 and ASK 1 (also designated MEK kinase-5). MEK kinase-1 has been shown to phosphorylate MEK-1 via a Raf-independent pathway. Evidence suggests that MEK-3 is preferentially activated by MEK kinase-3 and that MEK-4 is activated by both MEK kinase-2 and MEK kinase-3. MEK kinase-4 has been shown to specifically activate the JNK pathway. ASK1 activates both |
Immunogen | n/a |
Other Names | MAPKKK3, MEKK3, MAP/ERK kinase kinase 3, MAPK/ERK kinase kinase 3, MEK kinase 3, MEKK 3 |
Gene, Accession # | Entrez: 4215; Uniprot: Q99759 |
Catalog # | A303-133A-T |
Price | |
Order / More Info | MEKK3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
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