产品详情 |
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Antigenic Specificity | MEKK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:1,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MEKK1 Polyclonal Antibody. Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK1 can phosphorylate and activate MAPKK 1 and MAPKK 2 (MEK1/MEK2) which leads to phosphorylation of MAP kinases. It is also a highly efficient activator of the JNK cascade. The protein contains a putative 1 RING-type zinc finger and 1 SWIM-type zinc finger. |
Immunogen | n/a |
Other Names | Mitogen-activated protein kinase kinase kinase 1; MAPK/ERK kinase kinase 1; MEK kinase 1; MEKK 1; MAPKKK1; MEKK; MEKK1 |
Gene, Accession # | Entrez: 4214; Uniprot: Q13233 |
Catalog # | A302-395A-M |
Price | |
Order / More Info | MEKK1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
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