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| Product Name | Neutrophil (mouse) Isolation Kit |
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| Description | Neutrophils are short-lived inflammatory cells that are highly adept at ingesting and destroying bacteria as part of the first line of defense in the innate immune response to many pathogenic organisms. They produce an extensive arsenal of defensive antimicrobial proteins and peptides including lysozyme, myeloperoxidase, neutrophil elastase, cathepsins, and the alpha- and beta-defensins. Neutrophils also form extracellular traps, web-like structures composed of DNA, histones, and various antimicrobial proteins that are extruded from the neutrophil in order to ensnare and kill extracellular pathogens. In mice, neutrophils comprise ~10% of circulating white blood cells, so unlike humans, it is usually not possible to isolate even one million neutrophils from a single mouse from peripheral blood. Cayman's Neutrophil (mouse) Isolation Kit provides a streamlined method for isolating mouse neutrophils by peritoneal lavage. Included in this kit are all the reagents necessary for inducing a sterile inflammatory response in the peritoneal cavities of up to five mice, the density separation medium required to separate the neutrophils from other peritoneal leukocytes, and the fluorochrome-labeled antibodies required to assess the success of the isolation procedure by flow cytometry. |
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| Size | 1 ea |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | neutrophils isolations kits assays mouse mice inducing induces inductions sterile inflammatory inflammations responses peritoneals cavity cavities five 5 density densities separations media mediums separates peritoneal peritoneums parietal visceral leukocytes leucocytes WBCs white blood cells fluorochrome-labeled fluorochromes labels labeled antibody antibodies FC flow cytometrys |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 601070-1EA |
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| Order / More Info | Neutrophil (mouse) Isolation Kit from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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