| 产品详情 |
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| Product Name | Myriocin |
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| Description | Myriocin is an amino fatty acid antibiotic derived from certain thermophylic fungi, in this case Mycelia sterilia. It is a potent immunosuppressant having 10- to 100-fold more activity than cyclosporin A.{8482} Myriocin is a potent inhibitor of serine palmitoyltransferase (Ki = 0.28 nM), the enzyme that catalyzes the first step of sphingolipid biosynthesis. {14764} It disrupts substratum adhesion of melanoma cells.{14763} It also suppresses cell proliferation in the murine cytotoxic T cell line CTLL-2 (IC50 = 15 nM) via apoptosis.{14764,2816} Myriocin suppresses replication of the hepatitis C virus (HCV) in a murine model.{14762} |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ISP-1|Thermozymocidin |
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| Gene, Accession, CAS # | CAS: 35891-70-4 |
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| Catalog # | 63150-10 |
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| Price | |
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| Order / More Info | Myriocin from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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