| 产品详情 |
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| Antigenic Specificity | CD10 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | ascites |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | ELISA, WB, IHC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD10 (MME): membrane metallo-endopeptidase.This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL).This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL.This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues.It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb.The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts.The coding region is not affected by alternative splicing. |
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| Immunogen | Purified recombinant fragment of CD10 expressed in E. coli. |
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| Other Names | CD10; Common acute lymphoblastic leukemia antigen (CALLA); Enkephalinase; Neutral endopeptidase; Neprilysin; MAb to CD10; EPN; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Neutral endopeptidase 24.11; NEP; Skin fibroblast elastase; SFE; CD antigen CD10; MME |
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| Gene, Accession # | MME, Gene ID: 4311, SwissProt: P08473 |
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| Catalog # | abx015726 |
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| Price | |
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| Order / More Info | CD10 Antibody from ABBEXA |
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| Product Specific References | n/a |
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