产品名称 DC- LAMP/CD208 Antibody from DENDRITICS SAS
产品货号 DDX0193
产品价格 现货询价,电话:010-67529703
产品规格 100µg/50µg
产品品牌 DENDRITICS SAS
产品概述
产品详情
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Antigenic SpecificityDC- LAMP/CD208
Clone109G3
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatpurified
Size100µg/50µg
Concentrationn/a
ApplicationsIHC, FACS intracyto
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DescriptionThe dendritic cell lysosomal?associated membrane protein (DC?LAMP)/CD208 is a type I integral transmembrane glycoprotein mostly homologous to CD68, of about 45 kDa mw in the mouse and 90 kDa mw in humans (due to extensive glycosylation), with a bipartite C-terminal structure divided by a serine/proline rich region, a transmembrane domain and a conserved tyrosine?based lysosomal targeting motif in its cytoplasmic tail Initially cloned as a specific marker of human mature dendritic cells (DCs), DC-LAMP has been subsequently shown to be expressed in alveolar type II pneumocytes. In both cell types, the molecule is found in the limiting membrane of intracellular multi?lamellar bodies, known as MIIC (MHC class II compartments) in human mature DC and as pulmonary surfactant?containing lamellar bodies in type II pneumocytes. In the latter cell type, DC-LAMP expression is also detected at the cell surface. (de Saint-Vis B et al., 1998 Immunity , 9: 325-336)
Immunogenn/a
Other NamesDendritic cell lysosomal?associated membrane protein
Gene, Accession #n/a
Catalog #DDX0193
Price
Order / More InfoDC- LAMP/CD208 Antibody from DENDRITICS SAS
Product Specific Referencesn/a
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