| 产品详情 |
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| Antigenic Specificity | IL6R |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | IL6R Antibody is a Rabbit Polyclonal antibody against IL6R. Interleukin-6 (IL-6) is a pleiotropic cytokine produced by a variety of cells during infection, trauma, and immunological challenge (PMID: 8274730). IL-6 acts via a receptor complex consisting of two distinct membrane-bound glycoproteins, an 80-kDa IL-6-binding subunit (IL6R, CD126, gp80) and a 130-kDa signal-transducing element (gp130, CD130). After binding of IL-6 to membrane-bound IL6R, the complex of IL-6 and IL6R associates with gp130, thus activating the receptor (PMID: 9716487). Expression of gp130 is found in almost all organs while expression of IL6R is predominantly confined to hepatocytes and leukocyte subpopulations (monocytes, neutrophils, T cells, and B cells) (PMID: 11149892). Soluble form of IL6R has been found in human serum and urine. |
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| Immunogen | Recombinant protein of human IL6R. |
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| Other Names | IL6R; Interleukin-6 Receptor; IL6; IL-6; IL-6R; IL 6R; Interleukin 6 Receptor; IL-6 Receptor Subunit Alpha; Membrane Glycoprotein 80; CD126 Antigen; IL-6R 1; IL-6RA; Gp80; IL-6R Subunit Alpha; IL-6R-Alpha; IL-6R-1; CD126; IL6RA; IL6RQ; IL6Q |
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| Gene, Accession # | IL6R, Gene ID: 3570, SwissProt: P08887 |
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| Catalog # | abx001321 |
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| Price | |
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| Order / More Info | IL6R Antibody from ABBEXA |
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| Product Specific References | n/a |
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