| 产品详情 |
| Edit |   |
| Antigenic Specificity | ITM2C |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl |
| Concentration | n/a |
| Applications | WB. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity). This ITM2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human ITM2C. |
| Immunogen | Human ITM2C. |
| Other Names | E25; BRI3; E25C; ITM3; BRICD2C; ITM2C; Integral membrane protein 2C; Cerebral protein 14; Transmembrane protein BRI3; CT-BRI3 |
| Gene, Accession # | ITM2C, SwissProt: Q9NQX7 |
| Catalog # | abx029346 |
| Price | |
| Order / More Info | ITM2C Antibody from ABBEXA |
| Product Specific References | n/a |
| 产品资料 |
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