产品详情 |
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Antigenic Specificity | SIGLEC8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SIGLEC8 Polyclonal Antibody. Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]). |
Immunogen | n/a |
Other Names | SAF2, SIGLEC-8, SIGLEC8L, CDw329, SAF-2, sialic acid-binding Ig-like lectin 8, sialoadhesin family member 2 |
Gene, Accession # | Entrez: 27181; Uniprot: Q9NYZ4 |
Catalog # | PA5-31030 |
Price | |
Order / More Info | SIGLEC8 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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