产品详情 |
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Antigenic Specificity | SIGLEC7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 400 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SIGLEC7 Polyclonal Antibody. SIGLECs are cell surface proteins of the Ig superfamily. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. A large subgroup of SIGLECs share high homology with SIGLEC3 (CD33) and are localized to 19q13.4. The cDNA for the SLG gene encodes 2 variants, SLG-long (SLGL) and SLG-short (SLGS). The 595-amino acid SLGL protein contains a signal peptide and 2 V-set N-terminal Ig-like domains. The 477-amino acid SLGS protein has a weak signal sequence and, like most SIGLEC3-like SIGLECs, has only 1 V-set N-terminal Ig-like domain. Both variants contain 2 C2-set N-terminal Ig-like domains, a transmembrane domain, and a cytoplasmic tail with a putative ITIM and a putative SL |
Immunogen | n/a |
Other Names | AIRM1, CD328, CDw328, D-siglec, QA79, SIGLEC-7, p75, p75/AIRM1, AIRM-1, QA79 membrane protein, adhesion inhibitory receptor molecule 1, siglec-7, sialic acid binding immunoglobulin-like lectin 7, sialic acid-binding Ig-like lectin 7 |
Gene, Accession # | Entrez: 27036; Uniprot: Q9Y286 |
Catalog # | PA5-11679 |
Price | |
Order / More Info | SIGLEC7 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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