| 产品详情 |
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| Antigenic Specificity | SIGLEC7 |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | Flow Cytometry: 2.5 µg/1x10^6 cells, Immunohistochemistry: 5-15 µg/mL, Neutralization: 0.3-0.9 µg/mL, Western Blot: 0.1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SIGLEC7 Polyclonal Antibody. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a rol |
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| Immunogen | n/a |
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| Other Names | AIRM1, CD328, CDw328, D-siglec, QA79, SIGLEC-7, p75, p75/AIRM1, AIRM-1, QA79 membrane protein, adhesion inhibitory receptor molecule 1, siglec-7, sialic acid binding immunoglobulin-like lectin 7, sialic acid-binding Ig-like lectin 7 |
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| Gene, Accession # | Entrez: 27036; Uniprot: Q9Y286 |
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| Catalog # | PA5-47079 |
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| Price | |
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| Order / More Info | SIGLEC7 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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