| 产品详情 |
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| Product Name | BIX02189 |
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| Description | A potent inhibitor of both MEK5 and ERK5 (IC50s = 1.5 and 59 nM, respectively); minimally inhibits a panel of related kinases, including MEK1/2 and ERK1/2; blocks sorbitol-induced phosphorylation of ERK5, without affecting phosphorylation of ERK1/2, in HeLa cells |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1094614-85-3 biochemical inhibitor signal transduction intracellular signaling protein kinase neuroscience cancer cardiology angiogenesis apoptosis inhibit signal transduction MEK5 ERK5 MEK ERK MAP2K5 MAP-2K5 MAPK7 MAP-K7 pathway stress-induced neuronal survival neuron cardiac development BIX-02189 transcriptional activation transcription downstream MEF2C MEF-2C MEK1/2 MEK-1/2 ERK1/2 ERK-1/2 sorbitol-induced phosphorylation HeLa cell nerve growth factor-mediated neurite outgrowth myeloid differentiation |
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| Gene, Accession, CAS # | CAS: 1265916-41-3 |
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| Catalog # | 16999-10 |
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| Price | |
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| Order / More Info | BIX02189 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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