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| Antigenic Specificity | RAF1 (pS471) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | DB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. This RAF1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S471 of human RAF1. |
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| Immunogen | Human RAF1 (phospho-Ser471). |
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| Other Names | C-RAF; CRAF; Protein kinase raf 1; RAF proto-oncogene serine/threonine-protein kinase; RAF-1; RAF1; Similar to murine leukemia viral (V-raf-1) oncogene homolog 1; kinase Raf1; NS5; Proto-oncogene c-RAF; RAF |
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| Gene, Accession # | SwissProt: P04049 |
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| Catalog # | abx031948 |
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| Price | |
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| Order / More Info | RAF1 (pS471) Antibody from ABBEXA |
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| Product Specific References | n/a |
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