| 产品详情 |
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| Antigenic Specificity | Kir2.1 (KCNJ2) |
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| Clone | S112B-14 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat, rhesus monkey |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Kir2.1 (KCNJ2) Monoclonal Antibody (S112B-14). The KIR2 subunit family includes 2.1, 2.2, 2.3 and 2.4. Unlike G protein-coupled KIR3 subunits, KIR2.1 requires both phosphorylation by PKA and ATP hydrolysis for functional activity. KIR2.1 is expressed in the superior and inferior collicula and the pontine region of the brain, where it moderates synaptic transmission, like many other potassium channels. In the placenta, KIR2.1 is expressed throughout gestation in cytotrophoblast cells. In the kidney, KIR2.1 colocalizes with KIR5.1 in the proximal tubule. KIR2.1, 2.2 and 2.3 associate with the membrane-associated guanylate kinase synapseassociated protein 97 in the cerebellum and heart. Phosphorylation of KIR2.2 by protein kinase A inhibits th |
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| Immunogen | n/a |
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| Other Names | HHBIRK1, HHIRK1, HIRK 1, IRK1, KCNJ2, LQT7, SQT3, potassium inwardly rectifying channel J2 |
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| Gene, Accession # | Entrez: 16518, 29712, 3759, 574189; Uniprot: P35561, P63252, Q64273 |
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| Catalog # | MA5-27681 |
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| Order / More Info | Kir2.1 (KCNJ2) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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