产品详情 |
Edit |   |
Antigenic Specificity | Androgen Receptor |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 10 µL |
Concentration | n/a |
Applications | Immunoprecipitation: 2-10 µg/mg lysate |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Androgen Receptor Polyclonal Antibody. The androgen receptor (AR) is a member of the steroid-hormone receptor superfamily of nuclear receptors. The receptor is more than 90 kDa and has three major functional domains: the N-terminal domain, DNA-binding domain, and the androgen-binding domain. The androgen receptor is a ligand-activated transcription factor that binds active testosterone (T) and dihydrotestosterone (DHT). Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. The AR signaling pathway plays a key role in development and function of male reproductive organs, including the prostate and epididymis. |
Immunogen | n/a |
Other Names | AR, ANDR, Dihydrotestosterone receptor |
Gene, Accession # | Entrez: 367; Uniprot: P10275 |
Catalog # | A303-966A-T |
Price | |
Order / More Info | Androgen Receptor Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
|
|