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Antigenic Specificity | CD279 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | n/a |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RABBIT ANTI HUMAN CD279. This item detects CD279, a co-stimulatory molecule also known as programmed cell death-1 (PD-1). CD279 is a single-pass type 1 membrane protein belonging to the CD28 family, and functions mainly as a negative regulator of T-cell activation. CD279 has two specific ligands; CD274 (PD-L1) and CD273 (PD-L2), and their interaction is key in the balance between stimulatory and inhibitory signals needed for effective immune responses to microbes and self-tolerance. CD279 is ind |
Immunogen | A peptide corresponding to a 16 amino acid sequence from near the centre of Human CD279.Histology Positive Control Tissue: Human brain tissue |
Other Names | programmed cell death protein 1; Programmed cell death protein 1; programmed cell death protein 1; protein PD-1; systemic lupus erythematosus susceptibility 2; programmed cell death 1; CD_antigen: CD279, PDCD1; PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; PD1; Protein PD-1; hPD-1 |
Gene, Accession # | CD279, Gene ID: 5133, NCBI: NP_005009.2, UniProt: Q15116 |
Catalog # | MBS223817 |
Price | |
Order / More Info | CD279 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |