产品详情 |
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Antigenic Specificity | ASAP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Western Blot: 2.0-3 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ASAP1 Polyclonal Antibody. ASAP1, also known as Development and differentiation enhancing factor 1, is a protein with two ANK repeats, an Arf-GAP domain, a PH domain and a SH3 domain. ASAP1 is a homodimer known to interact with SRC and CRK and its activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2). It possesses phosphatidylinositol 4,5-biphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. It may coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2 and may also function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly ot |
Immunogen | n/a |
Other Names | AMAP1, CENTB4, DDEF1, PAG2, PAP, ZG14P, 130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein, 130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein, ADP-ribosylation factor-directed GTPase-activating protein 1, ARF GTPase-activating protein 1, DEF-1, PIP2-dependent ARF1 GAP, arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1, centaurin, beta 4, development and differentiation-enhancing factor 1 |
Gene, Accession # | Entrez: 13196; Uniprot: Q9QWY8 |
Catalog # | PA5-23323 |
Price | |
Order / More Info | ASAP1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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