产品名称 TLR7 Antibody from DENDRITICS SAS
产品货号 DDX0501
产品价格 现货询价,电话:010-67529703
产品规格 100µg/50µg
产品品牌 DENDRITICS SAS
产品概述
产品详情
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Antigenic SpecificityTLR7
Clone85D6
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a
Formatpurified
Size100µg/50µg
Concentrationn/a
ApplicationsFACS intracyto, IHC frozen section, IF
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionTLR7 very close to TLR8 are phylogenitically and structurally related members of TLRs family. At least twelve members of the Toll family have been identified. TLR7 is expressed on plasmacytoid DCs, B and T lymphocytes, neutrophils, eosinophils, NK cells, and lung and placenta epithelial cells. TLR7 is localized to endosomal/lysosomal compartments and is reported to respond to single-stranded RNA. Plasmacytoid DCs express TLR7 and respond to activation by producing high amounts of IFN-a / b. TLR7 ligands are R848, Imiquimod (Imidazoquinolin family) and loxoribine (guanosin analog). (Diebold S.S.et al, Science 2004, 303, 1529; Barchet W.A. et al, 2005, Eur J Immunol 3:236; Lund J.M. et al., 2004, PNAS 5598 ;Hell F. et al., 2004 Science, 303, 1526 ; Gilliet M et al.,2008, Natur Rev Immunol.8, 594).
Immunogenn/a
Other NamesToll-like receptor 7
Gene, Accession #n/a
Catalog #DDX0501
Price
Order / More InfoTLR7 Antibody from DENDRITICS SAS
Product Specific Referencesn/a
产品资料