产品名称 HIV-1 gp41 Antibody from DENDRITICS SAS
产品货号 DDX1305
产品价格 现货询价,电话:010-67529703
产品规格 100µg/50µg
产品品牌 DENDRITICS SAS
产品概述
产品详情
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Antigenic SpecificityHIV-1 gp41
Clone417D3.08
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatpurified
Size100µg/50µg
Concentrationn/a
ApplicationsFlow cytometry, Neutralization, Cell-coated ELISA, Inhibition of syncitia formation, Blocking of HR1/HR2 complex formation
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DescriptionHIV-1-gp41 is a subunit of the envelope protein complex of HIV. HIV-1-gp41 is responsible for the fusion between the viral and the cell membranes and thus represents a target for HIV vaccines. Trimeric Env is composed of gp120, which is non-covalently associated with the membrane-anchored fusion protein gp41. HIV-1 gp120 binding to CD4 and co-receptor (CCR5 or CXCR4) induces conformational changes, resulting in gp41 exposure and in the production of fusion-intermediate conformation of gp41 (HR1 and HR2). 3 neutralizing anti-gp41 monoclonal antibodies were selected from mice immunized with 293T cells stably transfected with a construct expressing HR1 plus HR2. (Dawood R et al, AIDS. 27(5):717-730, 2013).
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #DDX1305
Price
Order / More InfoHIV-1 gp41 Antibody from DENDRITICS SAS
Product Specific Referencesn/a
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